• Frontiers, 28 March 2019

    Title :Surfactant Protein D Reverses the Gene Signature of Transepithelial HIV-1 Passage and Restricts the Viral Transfer Across the Vaginal Barrier Abstract : Background: Effective prophylactic strategy against the current epidemic of sexually transmitted HIV-1 infection requires understanding of the innate gatekeeping mechanisms at the genital mucosa. Surfactant protein D (SP-D), a member of the […]

  • Scientific Reports, 7th February 2019

    Title : Comparative transcriptomics approach in elucidation of carotenoid biosynthesis regulation in grains of rice (OryzasativaL.) Abstract : Background: Estimation of phytoene, lycopene, β-carotene, lutein, and zeaxanthin in grains of white, brown and purple cultivars of rice revealed marked differences in the levels of these carotenoid intermediates amongst the cultivars. Grains of white rice did […]

  • BMC GENOMICS, 29th November 2018

    Title : A transcriptomic snapshot of early molecular communication between Pasteuriapenetransand Meloidogyne incognita Abstract : Background: Southern root-knot nematode Meloidogyne incognita (Kofoid and White, 1919), Chitwood, 1949 is a key pest of agricultural crops. Pasteuriapenetrans is a hyperparasitic bacterium capable of suppressing the nematode reproduction, and represents a typical coevolved pathogen-hyperparasite system. Attachment of Pasteuria […]

  • The Faseb Journal

    Title : Unraveling the role of aurora A beyond centrosomes and spindle assembly: implications in muscle differentiation. Abstract : Aurora kinases are critical mitotic serine/threonine kinases and are often implicated in tumorigenesis. Recent studies of the interphase functions for aurora kinase (Aurk)A have considerably expanded our understanding of its role beyond mitosis. To identify the […]

  • Probiotics and Antimicrobial Proteins

    Title : Probiotics L. acidophilus and B. clausii Modulate Gut Microbiota in Th1- and Th2-Biased Mice to Ameliorate Salmonella Typhimurium-Induced Diarrhea. Abstract : Gut microbiota play important role in maintaining health. Probiotics are believed to augment it further. We aimed at comparing effects of probiotics, Lactobacillus acidophilus (LA) and Bacillus clausii (BC) (a) on the […]

  • Frontiers in Plant Science, May 2018

    Title : ARMOUR – A Rice miRNA: mRNA Interaction Resource. Abstract : ARMOUR was developed as A Rice miRNA:mRNA interaction resource. This informative and interactive database includes the experimentally validated expression profiles of miRNAs under different developmental and abiotic stress conditions across seven Indian rice cultivars. This comprehensive database covers 689 known and 1664 predicted […]

  • Scientific Reports

    Title: Comparative genomic analysis of a naturally competent Elizabethkingia anophelis isolated from an eye infection. Abstract : Elizabethkingia anophelis has now emerged as an opportunistic human pathogen. However, its mechanisms of transmission remain unexplained. Comparative genomic (CG) analysis of E. anopheles endophthalmitis strain surprisingly found from an eye infection patient with twenty-five other E. anophelis […]

  • Scientific Reports, May 2018

    Title : Co-expression network analysis of toxin-antitoxin loci in Mycobacterium tuberculosis reveals key modulators of cellular stress. Abstract : Research on toxin-antitoxin loci (TA loci) is gaining impetus due to their ubiquitous presence in bacterial genomes and their observed roles in stress survival, persistence and drug tolerance. The present study investigates the expression profile of […]

  • Biochimie

    Title : Biological and regulatory rolesof acid-induced small RNA RyeC in Salmonella Typhimurium. Abstract : Salmonella Typhimurium is an enteric pathogen that has evolved masterful strategies to enable survival under stress conditions both within and outside a host. The acid tolerance response (ATR) is one such mechanism that enhances the viability of acid adapted bacteria […]

  • Genome Announcements

    Title : Draft Genome Sequence of Multidrug-Resistant Escherichia coli NIVEDI-P44, Isolated from a Chicken Fecal Sample in Northeast India. Abstract : We report here the draft genome sequence of a multidrug-resistant Escherichia coli strain (NIVEDI-P44) isolated from a chicken fecal sample. The estimated genome size is 4.76 Mb, with a G+C content of 50.65%. The […]

  • Scientific Reports, April 2018

    Title : Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning. Abstract : Rudhira/Breast Carcinoma Amplified Sequence 3 (BCAS3) is a cytoskeletal protein that promotes directional cell migration and angiogenesis in vitro and is implicated in human carcinomas and coronary artery disease. To study the role of Rudhira during development in vivo, we generated the […]

  • The Febs Journal

    Title : p53 mediated regulation ofcoactivator associated arginine methyltransferase 1 (CARM1) expression iscritical for suppression of adipogenesis. Abstract : Coactivator-associated arginine methyltransferase 1 (CARM1/PRMT4) is a type I arginine methyltransferase that mediates transcriptional activation via methylation of histone H3 on R17, R26, and R42. CARM1 is also a coactivator of transcription of various transcription factors […]

  • Molecular Therapy – Nucleic Acids, December 2017

    Title : Characterization andMolecular Mechanism of Peptide-Conjugated Gold Nanoparticle Inhibiting p53-HDM2Interaction in Retinoblastoma. Abstract: Inhibition of the interaction between p53 and HDM2 is an effective therapeutic strategy in cancers that harbor a wild-type p53 protein such as retinoblastoma (RB). Nanoparticle-based delivery of therapeutic molecules has been shown to be advantageous in localized delivery, including to […]

  • Hepatology

    Title : Global microRNA expressionprofiling in the liver biopsies of hepatitis B virus-infected patients suggestsspecific microRNA signatures for viral persistence and hepatocellular injury. Abstract : Hepatitis B virus (HBV) can manipulate the microRNA (miRNA) regulatory networks in infected cells to create a permissive environment for viral replication, cellular injury, disease onset, and its progression. The […]

  • Genome Announcements , October 2017

    Title : Draft Genome Sequence of Rhizoctonia solani Anastomosis Group 1 Subgroup 1AStrain 1802/KB Isolated from Rice. Abstract : Sheath blight, caused by Rhizoctonia solani anastomosis group 1 subgroup 1A (AG1-1A), is one of the most devastating rice diseases worldwide. Here, we report the draft genome sequence of R. solani AG1-1A strain 1802/KB isolated from […]

  • Plos One, October 2017

    Title : Identification of functionally important microRNAs from rice inflorescence at heading stage of a qDTY4.1-QTL bearing Near Isogenic Line under drought conditions. Abstract : A cross between IR64 (high-yielding but drought-susceptible) and Aday Sel (drought-tolerant) rice cultivars yielded a stable line with enhanced grain yield under drought screening field trials at International Rice Research […]

  • Scientific Reports , July 2017

    Title : Co-expressionnetwork analysis of toxin-antitoxin loci in Mycobacterium tuberculosis revealskey modulators of cellular stress. Abstract : Research on toxin-antitoxin loci (TA loci) is gaining impetus due to their ubiquitous presence in bacterial genomes and their observed roles in stress survival, persistence and drug tolerance. The present study investigates the expression profile of all the […]

  • Heliyon

    Title: miRNA signatures can predict acute liver failure in hepatitis E infected pregnant females Abstract: Acute viral hepatitis E (AVH-E) can often result in acute liver failure (ALF) during pregnancy. microRNAs serve as mediators in drug induced liver failure. We investigated their role as a biomarker in predicting ALF due to HEV (ALF-E). FINDINGS: Eleven […]

  • Molecular Oncology

    TITLE: Gene regulatory networking reveals the molecular cue to lysophosphatidic acid-induced metabolic adaptations in ovarian cancer cells. ABSTRACT: Extravasation and metastatic progression are two main reasons behind the high mortality rate associated with cancer. The metastatic potential of cancer cells depends on a plethora of metabolic challenges prevailing in the tumor microenvironment. To achieve higher proliferative rates, […]

  • Stem Cells Translational Medicine

    Title: EpCAM+ Liver Cancer Stem-Like Cells Exhibiting Autocrine Wnt Signaling Potentially Originate in Cirrhotic Patients. Abstract: Hepatocellular carcinoma (HCC) is believed to originate from cancer stem cells (CSCs). While epithelial cell adhesion molecule (EpCAM) is a marker of normal hepatic stem cells (HSCs), EpCAM+ cells from HCC behave like CSCs. Since HCC mostly develops on […]

  • Systems Biology in Reproductive Medicine

    TITLE: Age-related changes in gene expression patterns of immature and aged rat primordial follicles. ABSTRACT: Women are born with millions of primordial follicles which gradually decrease with increasing age and this irreversible supply of follicles completely exhausts at menopause. The fertility capacity of women diminishes in parallel with aging. The mechanisms for reproductive aging are […]

  • Scientific Reports

    TITLE: Transcriptional changes during ovule development in two genotypes of litchi (Litchi chinensis Sonn.) with contrast in seed size ABSTRACT: Litchi chinensis is a subtropical fruit crop, popular for its nutritional value and taste. Fruits with small seed size and thick aril are desirable in litchi. To gain molecular insight into gene expression that leads to […]


    TITLE: Transcriptome Analysis of the Response to NaCl in Suaeda maritima Provides an Insight into Salt Tolerance Mechanisms in Halophytes ABSTRACT: Although salt tolerance is a feature representative of halophytes, most studies on this topic in plants have been conducted on glycophytes. Transcriptome profiles are also available for only a limited number of halophytes. Hence, […]

  • Molecular Therapy – Nucleic Acids

    TITLE: Nucleolin-aptamer therapy in retinoblastoma: molecular changes and mass spectrometry–based imaging ABSTRACT: Retinoblastoma (RB) is an intraocular childhood tumor which, if left untreated, leads to blindness and mortality. Nucleolin (NCL) protein which is differentially expressed on the tumor cell surface, binds ligands and regulates carcinogenesis and angiogenesis. We found that NCL is over expressed in […]

  • Frontiers in Plant Sciences

    TITLE: De novo Assembly of Leaf Transcriptome in the Medicinal Plant Andrographis paniculata   ABSTRACT: Andrographis paniculata is an important medicinal plant containing various bioactive terpenoids and flavonoids. Despite its importance in herbal medicine, no ready-to-use transcript sequence information of this plant is made available in the public data base, this study mainly deals with […]

  • Journal of Investigative Dermatology

    TITLE: Notch1-MAPK Signaling Axis Regulates CD133+ Cancer Stem Cell-Mediated Melanoma Growth and Angiogenesis ABSTRACT: Functional characterization and understanding of the intricate signaling mechanisms in stem like cells is crucial for the development of effective therapies in melanoma. We have studied whether melanoma cells are phenotypically distinct and hierarchically organized according to their tumorigenic nature. We […]

  • Genome Announcement July 2016

    Title: Draft Genome Sequence of Acinetobacter sp. Strain BMW17, a Cellulolytic and Plant Growth-Promoting Bacterium Isolated from the Rhizospheric Region of Phragmites karka of Chilika Lake, India   Genome Announcement:  We report the 3.16 Mb draft genome of Acinetobacter sp. strain BMW17, a Gram-negative bacterium in the class of Gammaproteobacteria, isolated from the rhizospheric region […]

  • BioMed Central, 2014

    Genome wide screening of RNAi factors of Sf21 cells reveal several novel pathway associated proteins.

  • Biology of Reproduction, 2014

    Dramatic Changes in 67 MicroRNAs During Initiation of First Wave of Spermatogenesis in Mus musculus Testis:Global Regulatory Insights Generated by MicroRNA-mRNA Network Analysis.

  • BioMed Central, 2014

    Epigenetic response in mice mastitis: Role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection

  • PLoS One 2014

    De novo transcriptome sequencing and analysis of the cereal cyst nematode, Heterodera avenae.

  • Bioinform Biol Insights, 2013

    Identification and Insilico Analysis of Retinoblastoma Serum microRNA Profile and Gene Targets Towards Prediction of Novel Serum Biomarkers.

  • PLoS One. 2013

    Decreased pattern recognition receptor signaling, interferon-signature, and bactericidal/permeability-increasing protein gene expression in cord blood of term low birth weight human newborns.

  • J Thromb Haemost. 2013

    Nuclear factor (NF)-κB and its associated pathways are major molecular regulators of blood-induced joint damage in a murine model of hemophilia.

  • Stem Cell Rev. 2012

    Gene expression profiles and retinal potential of stem/progenitor cells derived from human iris and ciliary pigment epithelium.

  • Int J Mol Sci. 2012

    Pyrosequencing-Based Transcriptome Analysis of the Asian Rice Gall Midge Reveals Differential Response during Compatible and Incompatible Interaction

  • Curr Eye Res. 2012

    Microarray analysis and biochemical correlations of oxidative stress responsive genes in retinoblastoma.

  • Epigenetics. 2012

    Histone H3K14 and H4K8 hyperacetylation is associated with Escherichia coli-induced mastitis in mice.