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Minimal Residual Disease Monitoring: NGS as a promising tool for MRD detection for several hematological diseases. Author: Dr. Avrajit Chakraborty Image courtesy:  UPMC Health Beat Cancer treatment and recovery may have different stages depending on various clinical or physiological aspects. After completion of treatment, a patient can achieve “complete remission” where there is no presence […]

Title :Surfactant Protein D Reverses the Gene Signature of Transepithelial HIV-1 Passage and Restricts the Viral Transfer Across the Vaginal Barrier Abstract : Background: Effective prophylactic strategy against the current epidemic of sexually transmitted HIV-1 infection requires understanding of the innate gatekeeping mechanisms at the genital mucosa. Surfactant protein D (SP-D), a member of the […]

Title : Comparative transcriptomics approach in elucidation of carotenoid biosynthesis regulation in grains of rice (OryzasativaL.) Abstract : Background: Estimation of phytoene, lycopene, β-carotene, lutein, and zeaxanthin in grains of white, brown and purple cultivars of rice revealed marked differences in the levels of these carotenoid intermediates amongst the cultivars. Grains of white rice did […]

Title : A transcriptomic snapshot of early molecular communication between Pasteuriapenetransand Meloidogyne incognita Abstract : Background: Southern root-knot nematode Meloidogyne incognita (Kofoid and White, 1919), Chitwood, 1949 is a key pest of agricultural crops. Pasteuriapenetrans is a hyperparasitic bacterium capable of suppressing the nematode reproduction, and represents a typical coevolved pathogen-hyperparasite system. Attachment of Pasteuria […]

Title : Unraveling the role of aurora A beyond centrosomes and spindle assembly: implications in muscle differentiation. Abstract : Aurora kinases are critical mitotic serine/threonine kinases and are often implicated in tumorigenesis. Recent studies of the interphase functions for aurora kinase (Aurk)A have considerably expanded our understanding of its role beyond mitosis. To identify the […]

Title : Probiotics L. acidophilus and B. clausii Modulate Gut Microbiota in Th1- and Th2-Biased Mice to Ameliorate Salmonella Typhimurium-Induced Diarrhea. Abstract : Gut microbiota play important role in maintaining health. Probiotics are believed to augment it further. We aimed at comparing effects of probiotics, Lactobacillus acidophilus (LA) and Bacillus clausii (BC) (a) on the […]

Title : ARMOUR – A Rice miRNA: mRNA Interaction Resource. Abstract : ARMOUR was developed as A Rice miRNA:mRNA interaction resource. This informative and interactive database includes the experimentally validated expression profiles of miRNAs under different developmental and abiotic stress conditions across seven Indian rice cultivars. This comprehensive database covers 689 known and 1664 predicted […]

Title: Comparative genomic analysis of a naturally competent Elizabethkingia anophelis isolated from an eye infection. Abstract : Elizabethkingia anophelis has now emerged as an opportunistic human pathogen. However, its mechanisms of transmission remain unexplained. Comparative genomic (CG) analysis of E. anopheles endophthalmitis strain surprisingly found from an eye infection patient with twenty-five other E. anophelis […]