• Heliyon

    Title: miRNA signatures can predict acute liver failure in hepatitis E infected pregnant females Abstract: Acute viral hepatitis E (AVH-E) can often result in acute liver failure (ALF) during pregnancy. microRNAs serve as mediators in drug induced liver failure. We investigated their role as a biomarker in predicting ALF due to HEV (ALF-E). FINDINGS: Eleven […]

  • Molecular Oncology

    TITLE: Gene regulatory networking reveals the molecular cue to lysophosphatidic acid-induced metabolic adaptations in ovarian cancer cells. ABSTRACT: Extravasation and metastatic progression are two main reasons behind the high mortality rate associated with cancer. The metastatic potential of cancer cells depends on a plethora of metabolic challenges prevailing in the tumor microenvironment. To achieve higher proliferative rates, […]

  • Stem Cells Translational Medicine

    Title: EpCAM+ Liver Cancer Stem-Like Cells Exhibiting Autocrine Wnt Signaling Potentially Originate in Cirrhotic Patients. Abstract: Hepatocellular carcinoma (HCC) is believed to originate from cancer stem cells (CSCs). While epithelial cell adhesion molecule (EpCAM) is a marker of normal hepatic stem cells (HSCs), EpCAM+ cells from HCC behave like CSCs. Since HCC mostly develops on […]

  • Systems Biology in Reproductive Medicine

    TITLE: Age-related changes in gene expression patterns of immature and aged rat primordial follicles. ABSTRACT: Women are born with millions of primordial follicles which gradually decrease with increasing age and this irreversible supply of follicles completely exhausts at menopause. The fertility capacity of women diminishes in parallel with aging. The mechanisms for reproductive aging are […]

  • Scientific Reports

    TITLE: Transcriptional changes during ovule development in two genotypes of litchi (Litchi chinensis Sonn.) with contrast in seed size ABSTRACT: Litchi chinensis is a subtropical fruit crop, popular for its nutritional value and taste. Fruits with small seed size and thick aril are desirable in litchi. To gain molecular insight into gene expression that leads to […]


    TITLE: Transcriptome Analysis of the Response to NaCl in Suaeda maritima Provides an Insight into Salt Tolerance Mechanisms in Halophytes ABSTRACT: Although salt tolerance is a feature representative of halophytes, most studies on this topic in plants have been conducted on glycophytes. Transcriptome profiles are also available for only a limited number of halophytes. Hence, […]

  • Molecular Therapy – Nucleic Acids

    TITLE: Nucleolin-aptamer therapy in retinoblastoma: molecular changes and mass spectrometry–based imaging ABSTRACT: Retinoblastoma (RB) is an intraocular childhood tumor which, if left untreated, leads to blindness and mortality. Nucleolin (NCL) protein which is differentially expressed on the tumor cell surface, binds ligands and regulates carcinogenesis and angiogenesis. We found that NCL is over expressed in […]

  • Frontiers in Plant Sciences

    TITLE: De novo Assembly of Leaf Transcriptome in the Medicinal Plant Andrographis paniculata   ABSTRACT: Andrographis paniculata is an important medicinal plant containing various bioactive terpenoids and flavonoids. Despite its importance in herbal medicine, no ready-to-use transcript sequence information of this plant is made available in the public data base, this study mainly deals with […]

  • Journal of Investigative Dermatology

    TITLE: Notch1-MAPK Signaling Axis Regulates CD133+ Cancer Stem Cell-Mediated Melanoma Growth and Angiogenesis ABSTRACT: Functional characterization and understanding of the intricate signaling mechanisms in stem like cells is crucial for the development of effective therapies in melanoma. We have studied whether melanoma cells are phenotypically distinct and hierarchically organized according to their tumorigenic nature. We […]

  • Genome Announcement July 2016

    Title: Draft Genome Sequence of Acinetobacter sp. Strain BMW17, a Cellulolytic and Plant Growth-Promoting Bacterium Isolated from the Rhizospheric Region of Phragmites karka of Chilika Lake, India   Genome Announcement:  We report the 3.16 Mb draft genome of Acinetobacter sp. strain BMW17, a Gram-negative bacterium in the class of Gammaproteobacteria, isolated from the rhizospheric region […]

  • BioMed Central, 2014

    Genome wide screening of RNAi factors of Sf21 cells reveal several novel pathway associated proteins.

  • Biology of Reproduction, 2014

    Dramatic Changes in 67 MicroRNAs During Initiation of First Wave of Spermatogenesis in Mus musculus Testis:Global Regulatory Insights Generated by MicroRNA-mRNA Network Analysis.

  • BioMed Central, 2014

    Epigenetic response in mice mastitis: Role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection

  • PLoS One 2014

    De novo transcriptome sequencing and analysis of the cereal cyst nematode, Heterodera avenae.

  • Bioinform Biol Insights, 2013

    Identification and Insilico Analysis of Retinoblastoma Serum microRNA Profile and Gene Targets Towards Prediction of Novel Serum Biomarkers.

  • PLoS One. 2013

    Decreased pattern recognition receptor signaling, interferon-signature, and bactericidal/permeability-increasing protein gene expression in cord blood of term low birth weight human newborns.

  • J Thromb Haemost. 2013

    Nuclear factor (NF)-κB and its associated pathways are major molecular regulators of blood-induced joint damage in a murine model of hemophilia.

  • Stem Cell Rev. 2012

    Gene expression profiles and retinal potential of stem/progenitor cells derived from human iris and ciliary pigment epithelium.

  • Int J Mol Sci. 2012

    Pyrosequencing-Based Transcriptome Analysis of the Asian Rice Gall Midge Reveals Differential Response during Compatible and Incompatible Interaction

  • Curr Eye Res. 2012

    Microarray analysis and biochemical correlations of oxidative stress responsive genes in retinoblastoma.

  • Epigenetics. 2012

    Histone H3K14 and H4K8 hyperacetylation is associated with Escherichia coli-induced mastitis in mice.